Cyto Genetics

Chromosomal & Genetic Diagnostic Testing

Cytogenetics involves the study of chromosome structure, number, and behavior during cell division. Tapadia Diagnostic provides specialized genetic testing to detect chromosomal abnormalities associated with congenital disorders, developmental delays, recurrent pregnancy loss, and hematological malignancies.

Key Cytogenetic Testing Procedures

• Karyotyping (G-Banding): High-resolution microscopic examination of metaphase chromosomes to identify numerical anomalies (aneuploidies like Down syndrome, Turner syndrome, Klinefelter syndrome) and structural rearrangements (translocations, inversions).

• Prenatal Genetic Screening: Maternal serum double marker and quadruple marker tests combined with biochemical risk calculation algorithms.

• Recurrent Miscarriage & Infertility Evaluations: Peripheral blood constitutional karyotyping for couples experiencing recurrent pregnancy loss or unexplained infertility.

• Onco-Hematology Cytogenetics: Bone marrow and peripheral blood chromosomal profiling for leukemias and myelodysplastic syndromes.

Sample Requirements & Quality Protocol

Cytogenetic analyses require fresh peripheral blood, bone marrow aspirates, or tissue samples collected under strict sterile conditions with specified heparin anticoagulants. All cultures and karyograms are analyzed following international standard cytogenetic nomenclature (ISCN) guidelines.