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Osmotic (RBC) Fragility Test in Jaipur

Also called: RBC Fragility Test, OFT, Osmotic Fragility

SAMPLE
Peripheral Blood
Report
Same or next day
PREPARATIONS
Fasting for 8-12 hours preferred
CONTAINS
2 Parameters

The test at a glance

What it checks
The Osmotic Fragility Test measures red blood cell resistance to hemolysis under decreasing saline concentrations, diagnosing hereditary spherocytosis and erythrocyte membrane fragility.
Report delivery
Sample before 12 PM → by 8:30 PM today | Sample after 12 PM → by 1 PM tomorrow
Test for
Men, Women
Age group
All Ages
Commonly advised for
Hereditary spherocytosis, hemolytic anemia of unknown origin, red blood cell membrane defect evaluation, splenomegaly workup

What is a Osmotic (RBC) Fragility Test ?

Clinical Significance: The Osmotic Fragility Test measures red blood cell resistance to hemolysis under decreasing saline concentrations, diagnosing hereditary spherocytosis and erythrocyte membrane fragility.

Why It's Done:

  • Evaluate structural integrity and surface-area-to-volume ratio of red blood cells
  • Confirm spherocytic RBC hemolysis at higher saline concentrations than normal cells
  • Differentiate hereditary spherocytosis from autoimmune hemolytic conditions
  • Guide decisions regarding splenectomy in chronic hemolytic patients

Who should take this test

The Osmotic (RBC) Fragility Test is recommended for individuals experiencing:

  • Patients with recurrent hemolytic episodes, jaundice, and enlarged spleen (splenomegaly)
  • Family history of hereditary spherocytosis or hemolytic disorders
  • Unexplained gallstones at a young age or recurring dark urine
  • Confirmation of RBC membrane defects identified on peripheral blood smears

Osmotic (RBC) Fragility Test testing in Jaipur

Tapadia Diagnostic Centre in Jaipur offers NABL-accredited Osmotic (RBC) Fragility Test test from a Peripheral Blood sample(s). RBC Fragility Test, OFT, Osmotic Fragility is also prescribed for Hereditary spherocytosis, hemolytic anemia of unknown origin, red blood cell membrane defect evaluation, splenomegaly workup. Established in 1989, this doctor-led diagnostic centre ensures high accuracy. Home sample collection and walk-in facility available at our Jaipur center. Pay at the centre with no advance payment. Book online or visit us.

Frequently asked questions

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Osmotic (RBC) Fragility Test in Jaipur

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Four decades of practice A family-run diagnostic centre, trusted by doctors and households since 1989

Medically Reviewed by Qualified Biochemists

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