Osmotic (RBC) Fragility Test in Madurai
Also called: RBC Fragility Test, OFT, Osmotic Fragility
- SAMPLE
- Peripheral Blood
- Report
- Same or next day
- PREPARATIONS
- Fasting for 8-12 hours preferred
- CONTAINS
- 2 Parameters
The test at a glance
- What it checks
- The Osmotic Fragility Test measures red blood cell resistance to hemolysis under decreasing saline concentrations, diagnosing hereditary spherocytosis and erythrocyte membrane fragility.
- Report delivery
- Sample before 12 PM → by 8:30 PM today | Sample after 12 PM → by 1 PM tomorrow
- Test for
- Men, Women
- Age group
- All Ages
- Commonly advised for
- Hereditary spherocytosis, hemolytic anemia of unknown origin, red blood cell membrane defect evaluation, splenomegaly workup
What is a Osmotic (RBC) Fragility Test ?
Clinical Significance: The Osmotic Fragility Test measures red blood cell resistance to hemolysis under decreasing saline concentrations, diagnosing hereditary spherocytosis and erythrocyte membrane fragility.
Why It's Done:
- Evaluate structural integrity and surface-area-to-volume ratio of red blood cells
- Confirm spherocytic RBC hemolysis at higher saline concentrations than normal cells
- Differentiate hereditary spherocytosis from autoimmune hemolytic conditions
- Guide decisions regarding splenectomy in chronic hemolytic patients
Who should take this test
The Osmotic (RBC) Fragility Test is recommended for individuals experiencing:
- Patients with recurrent hemolytic episodes, jaundice, and enlarged spleen (splenomegaly)
- Family history of hereditary spherocytosis or hemolytic disorders
- Unexplained gallstones at a young age or recurring dark urine
- Confirmation of RBC membrane defects identified on peripheral blood smears
Osmotic (RBC) Fragility Test testing in Madurai
Tapadia Diagnostic Centre in Madurai offers NABL-accredited Osmotic (RBC) Fragility Test test from a Peripheral Blood sample(s). RBC Fragility Test, OFT, Osmotic Fragility is also prescribed for Hereditary spherocytosis, hemolytic anemia of unknown origin, red blood cell membrane defect evaluation, splenomegaly workup. Established in 1989, this doctor-led diagnostic centre ensures high accuracy. Home sample collection and walk-in facility available at our Madurai center. Pay at the centre with no advance payment. Book online or visit us.
Frequently asked questions
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Osmotic (RBC) Fragility Test in Madurai
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